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Benzene image
71-43-2

Benzene

ALSO CALLED (6)Annulene, [6]Annulene, {[6]Annulene}, 1,3,5-cyclohexatriene, 1053658-43-7, 1173023-23-8, 174973-6...
Group I Human
Group II and II* Human
Ecotox
Fate
Physical
Mult
Non-GSLT
Carcinogenicity: High hazard (High confidence)
Mutagenicity/Genotoxicity: High hazard (High confidence)
Reproductive Toxicity: High hazard (High confidence)
Developmental Toxicity incl. developmental neurotoxicity: Moderate hazard (High confidence)
Endocrine Activity: Moderate hazard (Low confidence)
Acute Mammalian Toxicity: Low hazard (High confidence)
Systemic Toxicity/Organ Effects-Single Exposure: High hazard (High confidence)
Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure: High hazard (High confidence)
Neurotoxicity-Single Exposure: Moderate hazard (High confidence)
Neurotoxicity-Repeated Exposure: High hazard (High confidence)
Skin Sensitization: Low hazard (High confidence)
Respiratory Sensitization: Low hazard (Low confidence)
Skin Irritation/Corrosivity: High hazard (High confidence)
Eye Irritation/Corrosivity: High hazard (High confidence)
Acute Aquatic Toxicity: High hazard (High confidence)
Chronic Aquatic Toxicity: High hazard (High confidence)
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Persistence: Very low hazard (High confidence)
Bioaccumulation: Very low hazard (High confidence)
Reactivity: Low hazard (Low confidence)
Flammability: High hazard (High confidence)
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R
All Hazards
Carcinogenicity: High hazard (High confidence)
Mutagenicity/Genotoxicity: High hazard (High confidence)
Reproductive Toxicity: High hazard (High confidence)
Developmental Toxicity incl. developmental neurotoxicity: High hazard (High confidence)
Endocrine Activity: High to moderate hazard (Low confidence)
Acute Mammalian Toxicity: Very high hazard (Low confidence)
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Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure: High hazard (High confidence)
Neurotoxicity-Single Exposure: Potential concern hazard
Neurotoxicity-Repeated Exposure: Very high to moderate hazard (Low confidence)
Skin Sensitization: Potential concern hazard
Respiratory Sensitization: Moderate hazard
Skin Irritation/Corrosivity: High hazard (High confidence)
Eye Irritation/Corrosivity: High hazard (High confidence)
Acute Aquatic Toxicity: High hazard (Low confidence)
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Persistence: Very high to high hazard (Low confidence)
Bioaccumulation: Potential concern hazard
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Flammability: High hazard (High confidence)
List specifies multiple endpoints: Very high hazard (Low confidence)
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R
PubMed Results   - - -

Hazard Lists (25 endpoints)

Endpoint Hazard Level GS Score List Name Hazard Description Other Lists
Carcinogenicity
Carcinogenicity: High hazard (High confidence)
Carcinogen
Carcinogenicity: High hazard (High confidence)
Carcinogen Category 1A - Known human Carcinogen based on human evidence
Carcinogenicity: High hazard (High confidence)
H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
Carcinogenicity: High hazard (High confidence)
Carcinogen Category 1 - Substances known to be Carcinogenic to man
Carcinogenicity: High hazard (High confidence)
Group 1 - Agent is Carcinogenic to humans
Carcinogenicity: High hazard (High confidence)
Carcinogen Group 1 - Substances that cause cancer in man
Carcinogenicity: High hazard (High confidence)
Occupational Carcinogen
Carcinogenicity: High hazard (High confidence)
(1986) Group A - Human Carcinogen
Carcinogenicity: High hazard (High confidence)
(1996) Known/likely human Carcinogen
Carcinogenicity: High hazard (High confidence)
Known to be a human Carcinogen
Carcinogenicity: High hazard (Low confidence)
H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
Carcinogenicity: High hazard (Low confidence)
H350 - May cause cancer [Carcinogenicity - Category 1A]
Carcinogenicity: High hazard (Low confidence)
H350 - May cause cancer [Carcinogenicity - Category 1]
Carcinogenicity: High hazard (Low confidence)
H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
Carcinogenicity: High hazard (Low confidence)
Carcinogenicity category 1
Carcinogenicity: High hazard
Known human carcinogen - TSCA Criteria met
Carcinogenicity: Potential concern hazard
H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]
Carcinogenicity: Potential concern hazard
Chemicals that increased mammary gland tumors in animal studies
Mutagenicity/Genotoxicity
Mutagenicity/Genotoxicity: High hazard (High confidence)
Mutagen - Category 1B
Mutagenicity/Genotoxicity: High hazard (High confidence)
H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
Mutagenicity/Genotoxicity: High hazard (High confidence)
Mutagen Category 2 - Substances which should be regarded as if they are Mutagenic to man
Mutagenicity/Genotoxicity: High to moderate hazard (Low confidence)
Germ Cell Mutagen 3a
Mutagenicity/Genotoxicity: High hazard (Low confidence)
H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
Mutagenicity/Genotoxicity: High hazard (Low confidence)
H340 - May cause genetic defects [Germ cell mutagenicity - Category 1]
Mutagenicity/Genotoxicity: High hazard (Low confidence)
H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
Mutagenicity/Genotoxicity: High hazard (Low confidence)
Germ cell mutagenicity category 1
Mutagenicity/Genotoxicity: Moderate hazard (Low confidence)
H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
Mutagenicity/Genotoxicity: Potential concern hazard
H340 - May cause genetic defects (unverified) [Germ cell mutagenicity - Category 1A or 1B]
Reproductive Toxicity
Reproductive Toxicity: High hazard (High confidence)
Reproductive Toxicity - Male
Reproductive Toxicity: High hazard (Low confidence)
Reproductive toxicity category 1
Reproductive Toxicity: Moderate hazard (Low confidence)
H361 - Suspected of damaging fertility or the unborn child [Toxic to reproduction - Category 2]
Developmental Toxicity incl. developmental neurotoxicity
Developmental Toxicity incl. developmental neurotoxicity: High hazard (High confidence)
Developmental toxicity
Endocrine Activity
Endocrine Activity: High to moderate hazard (Low confidence)
Potential Endocrine Disruptor
Acute Mammalian Toxicity
Acute Mammalian Toxicity: Very high hazard (Low confidence)
Acute dermal toxicity category 2
Acute Mammalian Toxicity: Moderate hazard (Low confidence)
H302 - Harmful if swallowed [Acute Toxicity (oral) - Category 4]
Acute Mammalian Toxicity: Moderate hazard (Low confidence)
Acute oral toxicity category 4
Acute Mammalian Toxicity: High hazard
H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Acute Mammalian Toxicity: High hazard
H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Acute Mammalian Toxicity: Potential concern hazard
FIFRA Registered Pesticide
Acute Mammalian Toxicity: Potential concern hazard
H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Acute Mammalian Toxicity: Potential concern hazard
H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure
Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure: High hazard (High confidence)
H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure: High hazard (Low confidence)
H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure: Potential concern hazard
H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]
Neurotoxicity-Single Exposure
Neurotoxicity-Single Exposure: Potential concern hazard
H336 - May cause drowsiness or dizziness (unverified) [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]
Neurotoxicity-Repeated Exposure
Neurotoxicity-Repeated Exposure: Very high to moderate hazard (Low confidence)
Neurotoxic
Skin Sensitization
Skin Sensitization: Potential concern hazard
Potential Skin Allergens
Respiratory Sensitization
Respiratory Sensitization: Moderate hazard
Asthma - irritant - limited evidence
Skin Irritation/Corrosivity
Skin Irritation/Corrosivity: High hazard (High confidence)
H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
Skin Irritation/Corrosivity: High hazard (Low confidence)
H315 - Causes skin irritation [Skin corrosion / irritation - Category 2]
Skin Irritation/Corrosivity: High hazard (Low confidence)
H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
Skin Irritation/Corrosivity: High hazard (Low confidence)
H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
Skin Irritation/Corrosivity: High hazard (Low confidence)
H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
Skin Irritation/Corrosivity: High hazard (Low confidence)
Skin irritation category 2
Skin Irritation/Corrosivity: Potential concern hazard
H315 - Causes skin irritation (unverified) [Skin corrosion/irritation - Category 2]
Eye Irritation/Corrosivity
Eye Irritation/Corrosivity: High hazard (High confidence)
H319 - Causes serious eye irritation [Serious eye damage/eye irritation - Category 2A]
Eye Irritation/Corrosivity: High hazard (Low confidence)
H319 - Causes serious eye irritation [Serious eye damage / eye irritation - Category 2A]
Eye Irritation/Corrosivity: High hazard (Low confidence)
H319 - Causes serious eye irritation [Serious eye damage/irritation - Category 2]
Eye Irritation/Corrosivity: High hazard (Low confidence)
H319 - Causes serious eye irritation [Serious eye damage/eye irritation - Category 2A]
Eye Irritation/Corrosivity: High hazard (Low confidence)
H319 - Causes serious eye irritation [Serious eye damage/eye irritation - Category 2A]
Eye Irritation/Corrosivity: High hazard (Low confidence)
Eye irritation category 2
Eye Irritation/Corrosivity: Potential concern hazard
H319 - Causes serious eye irritation (unverified) [Serious eye damage/eye irritation - Category 2A]
Acute Aquatic Toxicity
Acute Aquatic Toxicity: High hazard (Low confidence)
H401 - Toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 2]
Persistence
Persistence: Very high to high hazard (Low confidence)
Persistent
Persistence: Potential concern hazard
Low environmental persistence - TSCA Criteria met
Bioaccumulation
Bioaccumulation: Potential concern hazard
Low bioaccumulation potential - TSCA Criteria met
Flammability
Flammability: High hazard (High confidence)
H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
Flammability: High hazard (Low confidence)
H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
Flammability: High hazard (Low confidence)
H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
Flammability: High hazard (Low confidence)
H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
Flammability: High hazard (Low confidence)
H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
Flammability: High hazard (Low confidence)
Flammable liquids category 2
Flammability: Very high to moderate hazard (Low confidence)
Class B2 - Flammable liquids
Flammability: Potential concern hazard
H225 - Highly flammable liquid and vapour (unverified) [Flammable liquids - Category 2]
Systemic Toxicity/Organ Effects (Single Exposure - Aspiration Hazard)
Systemic Toxicity/Organ Effects (Single Exposure - Aspiration Hazard): High hazard (High confidence)
H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Systemic Toxicity/Organ Effects (Single Exposure - Aspiration Hazard): Potential concern hazard
H304 - May be fatal if swallowed and enters airways (unverified) [Aspiration hazard - Category 1]
Human and/or Aquatic toxicity and/or Persistence and/or Bioaccumulation
Human and/or Aquatic toxicity and/or Persistence and/or Bioaccumulation: Unspecified hazard (Low confidence)
CEPA Toxics
Human and/or Aquatic toxicity and/or Persistence and/or Bioaccumulation: Unspecified hazard (Low confidence)
Class 3 - Severe Hazard to Waters
T & P and/or B [(Chronic Aquatic Toxicity and sometimes Persistence) or (Acute Aquatic Toxicity and Persistence and/or Bioaccumulation)]
T & P and/or B [(Chronic Aquatic Toxicity and sometimes Persistence) or (Acute Aquatic Toxicity and Persistence and/or Bioaccumulation)]: Unspecified hazard (Low confidence)
H411 - Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 2]
T & P and/or B [(Chronic Aquatic Toxicity and sometimes Persistence) or (Acute Aquatic Toxicity and Persistence and/or Bioaccumulation)]: Unspecified hazard (Low confidence)
H411 - Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 2]
Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]
Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]: High hazard (Low confidence)
H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]
Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]: High hazard (Low confidence)
H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - Repeated exposure - Category 1]
Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]: High hazard (Low confidence)
H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]: High hazard (Low confidence)
Specific target organ toxicity - repeated exposure category 1
Carcinogenicity,Mutagenicity/Genotoxicity Reproductive Toxicity, Developmental Toxicity, Acute Mammalian Toxicity, or System Toxicity/Organ Effects.
Carcinogenicity,Mutagenicity/Genotoxicity Reproductive Toxicity, Developmental Toxicity, Acute Mammalian Toxicity, or System Toxicity/Organ Effects.: Unspecified hazard (Low confidence)
Class D2A - Very toxic material causing other toxic effects
Carcinogenicity,Mutagenicity/Genotoxicity Reproductive Toxicity, Developmental Toxicity, Acute Mammalian Toxicity, or System Toxicity/Organ Effects.: Unspecified hazard (Low confidence)
Class D2B - Toxic material causing other toxic effects
Systemic Toxicity/Organ Effects [Single Exposure] and/or Neurotoxicity [Single Exposure]
Systemic Toxicity/Organ Effects [Single Exposure] and/or Neurotoxicity [Single Exposure]: Very high hazard (Low confidence)
H370 - Causes damage to organs [Specific target organs/systemic toxicity following single exposure - Category 1]
T & P and/or B [(Chronic Aquatic Toxicity and Persistence) or (Acute Aquatic Toxicity and Persistence and/or Bioaccumulation)]
T & P and/or B [(Chronic Aquatic Toxicity and Persistence) or (Acute Aquatic Toxicity and Persistence and/or Bioaccumulation)]: Potential concern hazard
H412 - Harmful to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 3]
Carcinogenicity, Mutagenicity/Genotoxicity Reproductive Toxicity and/or Developmental Toxicity
Carcinogenicity, Mutagenicity/Genotoxicity Reproductive Toxicity and/or Developmental Toxicity: Unspecified hazard (Low confidence)
CMR - Carcinogen, Mutagen &/or Reproductive Toxicant
Endpoint Hazard Level Hazard List Hazard Description Other Lists
Cancer: Priority level: Red (Very High concern to avoid)
High
Carcinogen
High Carcinogen Category 1A - Known human Carcinogen based on human evidence
High H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
High Carcinogen Category 1 - Substances known to be Carcinogenic to man
High Group 1 - Agent is Carcinogenic to humans
High Carcinogen Group 1 - Substances that cause cancer in man
High Occupational Carcinogen
High (1986) Group A - Human Carcinogen
High (1996) Known/likely human Carcinogen
High Known to be a human Carcinogen
High H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
High H350 - May cause cancer [Carcinogenicity - Category 1A]
High H350 - May cause cancer [Carcinogenicity - Category 1]
High H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
High Carcinogenicity category 1
High Known human carcinogen - TSCA Criteria met
Potential Concern H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]
Potential Concern Chemicals that increased mammary gland tumors in animal studies
Developmental: Priority level: Red (Very High concern to avoid)
High
Developmental toxicity
Reproductive: Priority level: Red (Very High concern to avoid)
High
Reproductive Toxicity - Male
High Reproductive toxicity category 1
Medium H361 - Suspected of damaging fertility or the unborn child [Toxic to reproduction - Category 2]
Gene mutation: Priority level: Red (Very High concern to avoid)
High
Mutagen - Category 1B
High H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
High Mutagen Category 2 - Substances which should be regarded as if they are Mutagenic to man
Medium Germ Cell Mutagen 3a
High H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
High H340 - May cause genetic defects [Germ cell mutagenicity - Category 1]
High H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
High Germ cell mutagenicity category 1
Medium H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
Potential Concern H340 - May cause genetic defects (unverified) [Germ cell mutagenicity - Category 1A or 1B]
Persistent: Priority level: Red (Very High concern to avoid)
High
Persistent
Potential Concern Low environmental persistence - TSCA Criteria met
Endocrine: Priority level: Orange (High concern to avoid)
Medium
Potential Endocrine Disruptor
Mammalian: Priority level: Orange (High concern to avoid)
High
H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Very High Acute dermal toxicity category 2
Medium H302 - Harmful if swallowed [Acute Toxicity (oral) - Category 4]
Medium Acute oral toxicity category 4
High H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
High H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Potential Concern FIFRA Registered Pesticide
Potential Concern H304 - May be fatal if swallowed and enters airways (unverified) [Aspiration hazard - Category 1]
Potential Concern H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Potential Concern H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Organ toxicant: Priority level: Orange (High concern to avoid)
High
H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
Very High H370 - Causes damage to organs [Specific target organs/systemic toxicity following single exposure - Category 1]
High H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
High H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]
High H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - Repeated exposure - Category 1]
High H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
High Specific target organ toxicity - repeated exposure category 1
Potential Concern H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]
Acute aquatic: Priority level: Orange (High concern to avoid)
High
H401 - Toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 2]
Chron aquatic: Priority level: Orange (High concern to avoid)
High
H411 - Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 2]
Medium H411 - Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 2]
Potential Concern H412 - Harmful to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 3]
Flammable: Priority level: Orange (High concern to avoid)
High
H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
High H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
High H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
High H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
High H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
High Flammable liquids category 2
Potential Concern Class B2 - Flammable liquids
Potential Concern H225 - Highly flammable liquid and vapour (unverified) [Flammable liquids - Category 2]
Respiratory: Priority level: Yellow (Moderate concern to avoid)
Medium
Asthma - irritant - limited evidence
Eye irritation: Priority level: Yellow (Moderate concern to avoid)
High
H319 - Causes serious eye irritation [Serious eye damage/eye irritation - Category 2A]
High H319 - Causes serious eye irritation [Serious eye damage / eye irritation - Category 2A]
High H319 - Causes serious eye irritation [Serious eye damage/irritation - Category 2]
High H319 - Causes serious eye irritation [Serious eye damage/eye irritation - Category 2A]
High H319 - Causes serious eye irritation [Serious eye damage/eye irritation - Category 2A]
High Eye irritation category 2
Potential Concern H319 - Causes serious eye irritation (unverified) [Serious eye damage/eye irritation - Category 2A]
Skin irritation: Priority level: Yellow (Moderate concern to avoid)
High
H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
High H315 - Causes skin irritation [Skin corrosion / irritation - Category 2]
High H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
High H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
High H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
High Skin irritation category 2
Potential Concern H315 - Causes skin irritation (unverified) [Skin corrosion/irritation - Category 2]
Multiple: Priority level: Yellow (Moderate concern to avoid)
Medium
Class D2A - Very toxic material causing other toxic effects
Medium Class D2B - Toxic material causing other toxic effects
Potential Concern CMR - Carcinogen, Mutagen &/or Reproductive Toxicant
Potential Concern CEPA Toxics
Potential Concern Class 3 - Severe Hazard to Waters
Skin sensitize: Priority level: Blue (Potential concern. Included on a Restricted Substances List for avoidance, monitoring, or careful management)
Potential Concern
Potential Skin Allergens
Restricted list: Priority level: Blue (Potential concern. Included on a Restricted Substances List for avoidance, monitoring, or careful management)
Potential Concern
Miscellaneous
Potential Concern Restrictions in Manufacturing Processes
Potential Concern 2019 Substance of Concern List
Potential Concern V3 2014 Substance of Concern List
Potential Concern Core Restrictions
Potential Concern Cosmetics & Personal Care Products
Potential Concern Candidate Chemical List
Potential Concern Chemicals of Concern
Potential Concern Priority Chemicals
Potential Concern Limit of harmful substances in industrial protective coatings (GB 30981-2020)
Potential Concern Limit standard for volatile organic compounds content in adhesives (GB 33372-2020)
Potential Concern Limit standard for volatile organic compounds content in cleaning agents (GB 38508-2020)
Potential Concern Limit standard for volatile organic compounds content in printing inks (GB 38507-2020)
Potential Concern CoHC List (non SVHC)
Potential Concern Prohibited Chemicals
Potential Concern Annex II - Prohibited Substances
Potential Concern Substances selected for RMOA or hazard assessment
Potential Concern Substances restricted under REACH
Potential Concern Food Contact Chemicals Database Version 5.0
Potential Concern Food Contact Chemicals of Concern List (FCCoCL)
Potential Concern Food Contact Chemicals of Concern List (FCCoCL) - TIER 2
Potential Concern FPF Priority Substance List from FCCdb
Potential Concern FSAP Food Packaging Product Stewardship Considerations
Potential Concern Restrictions for Manufacturing Process
Potential Concern Solvents
Potential Concern ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0
Potential Concern Food Packaging Forum Priority Substances List
Potential Concern ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0
Potential Concern ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0
Potential Concern Some Solvents
Potential Concern Ingredients that are Prohibited for Use in Cosmetic Products
Potential Concern Prohibition
Potential Concern Specification
Potential Concern Reportable Chemicals
Potential Concern Chemicals of High Concern
Potential Concern Chemicals of High Concern
Potential Concern Chemicals of high concern
Potential Concern Substances of Very High Concern (RIVM ZZS)
Potential Concern TSCA Chemical Substance Inventory - Active
Potential Concern HAPs subject to the Clean Air Act
Potential Concern Cancer causing substances subject to workplace management or avoidance
Potential Concern Chemicals of High Concern to Children
Potential Concern Chemicals of High Concern to Children
Potential Concern ZDHC - MRSL v1.1 for Natural Leather Processing
Potential Concern ZDHC - MRSL v1.1 for Textiles and Synthetic Leather Processing
Potential Concern ZDHC - MRSL v2.0
Neurotoxicity: Priority level: Grey (Wide range of possible hazard levels)
Potential Concern
Neurotoxic
Potential Concern H336 - May cause drowsiness or dizziness (unverified) [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]
Bioaccumulative: Priority level: Grey (Wide range of possible hazard levels)
Potential Concern
Low bioaccumulation potential - TSCA Criteria met

Cradle to Cradle Certified™ List Hazards

Acute and Chronic Tox. Acute Aquatic Tox. Chronic Aquatic Tox.
Carcinogenicity Mutagenicity Reproductive Toxicity (Repro + Dev) Endocrine Disruption Oral Toxicity Dermal Toxicity Inhalative Toxicity Oral, Dermal, and/or Inhalative Toxicity Neurotoxicity Skin, Eye, and Respiratory Corrosion/Irritation Skin and Respiratory Sensitization Acute Aquatic Toxicity (Fish) Acute Aquatic Toxicity (Invertibrates) Acute Aquatic Toxicity (Algae) Acute Aquatic Toxicity (Fish, Invertibrates, and/or Algae) Chronic Aquatic Toxicity (Fish) Chronic Aquatic Toxicity (Invertibrates) Chronic Aquatic Toxicity (Algae) Chronic Aquatic Toxicity (Fish, Invertibrates, and/or Algae) Terrestrial Persistence Bioaccumulation Climatic Relevance Organohalogen Toxic Metal Other (Human Health) Multiple Endpoints
Carcinogen
Mutagen - Category 1B
Developmental toxicity
Potential Endocrine Disruptor
H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]
Not listed on any C2C or Pharos hazard lists
Not listed on any C2C or Pharos hazard lists
H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
Neurotoxic
H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]
On a hazard list that has not been rated by C2C
Not listed on any C2C or Pharos hazard lists
Not listed on any C2C or Pharos hazard lists
Not listed on any C2C or Pharos hazard lists
H401 - Toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 2]
Not listed on any C2C or Pharos hazard lists
Not listed on any C2C or Pharos hazard lists
Not listed on any C2C or Pharos hazard lists
H411 - Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 2]
Not listed on any C2C or Pharos hazard lists
Persistent
On a hazard list that has not been rated by C2C
No Hazards Found
This chemical is not on the Pharos list of organohalogens, but we may have missed a few. Please double-check the chemical structure to confirm there are no carbon-halogen bonds.
This chemical is not on the Pharos list of toxic metals, but we may have missed a few. Please double-check the chemical structure to confirm there are no toxic metals.
H225 - Highly flammable liquid and vapour [Flammable liquids - Category 2]
CMR - Carcinogen, Mutagen &/or Reproductive Toxicant

Full Hazard List By Endpoint

Endpoint Lists
Carcinogenicity
Mutagenicity
Reproductive Toxicity (Repro + Dev)
Endocrine Disruption
Oral Toxicity
Dermal Toxicity not listed
Inhalative Toxicity not listed
Oral, Dermal, and/or Inhalative Toxicity
Neurotoxicity
Skin, Eye, and Respiratory Corrosion/Irritation
Skin and Respiratory Sensitization
Acute Aquatic Toxicity (Fish) not listed
Acute Aquatic Toxicity (Invertibrates) not listed
Acute Aquatic Toxicity (Algae) not listed
Acute Aquatic Toxicity (Fish, Invertibrates, and/or Algae)
Chronic Aquatic Toxicity (Fish) not listed
Chronic Aquatic Toxicity (Invertibrates) not listed
Chronic Aquatic Toxicity (Algae) not listed
Chronic Aquatic Toxicity (Fish, Invertibrates, and/or Algae)
Terrestrial not listed
Persistence
Bioaccumulation
Climatic Relevance not listed
Organohalogen not listed - This chemical is not on the Pharos list of organohalogens, but we may have missed a few. Please double-check the chemical structure to confirm there are no carbon-halogen bonds.
Toxic Metal not listed - This chemical is not on the Pharos list of toxic metals, but we may have missed a few. Please double-check the chemical structure to confirm there are no toxic metals.
Other (Human Health)
Multiple Endpoints

Restricted Substance Lists (46)

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