CHE - Toxicant Database

Toxicant and Disease Database
CHE is a project of Commonweal, a health and environmental research institute in Bolinas, CA. ...

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CHE is a project of Commonweal, a health and environmental research institute in Bolinas, CA.  Their Toxicant and Disease Database summarizes links between chemicals and more than 200 human diseases or conditions, of which sensitizer- and irritant-induced asthma are included. The database focuses primarily on human epidemiological studies, and a comprehensive review of animal data was beyond the scope of this project. However, in some instances animal data were included and influenced the listing. This is particularly likely when an authoritative body, such as the International Agency for Research on Cancer (IARC), the National Toxicology Program, or California’s Office of Environmental Health Hazard Assessment (OEHHA), which administers the Proposition 65 program, used animal data as the primary source for their evaluations.

The chemicals are listed in connection with a disease/ disorder and are then grouped by the strength of evidence available: strong (S), good (G), or (L) limited/ conflicting evidence. The database and its limitations, are further described here: https://www.healthandenvironment.org/our-work/toxicant-and-disease-database/about-the-toxicant-and-disease-database

Agency
Collaborative on Health and the Environment (CHE)
Updated
2017-12-26
Website
https://www.healthandenvironment.org/our-work/toxicant-and-disease-dat...
Hazards for Hazard List
Endpoint Hazard Rating and Description GS Score HPD C2C
Respiratory Sensitization
H
Asthma - allergen, sensitizer - strong evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
H
Asthma - allergen, sensitizer - good evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
H
Asthma - irritant - strong evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
H
Asthma - irritant - good evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
H
Rhinitis – allergic - strong evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
H
Rhinitis – allergic - good evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
H
Rhinitis – irritant- strong evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
H
Rhinitis – irritant- good evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
M
Asthma - allergen, sensitizer - limited evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
M
Asthma - irritant - limited evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
M
Rhinitis – allergic - limited evidence NoGS Skin and Respiratory Sensitization
Respiratory Sensitization
M
Rhinitis – irritant- limited evidence NoGS Skin and Respiratory Sensitization

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