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US EPA - PPT Chemical Action Plans

Risk Management Actions & TSCA Work Plans

EPA links currently in flux. They will be updated as they become available. This list is...

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EPA links currently in flux. They will be updated as they become available.

This list is compiled from four EPA lists: 

EPA established a group of “Chemicals of Concern” consisting of chemical groups raising serious health or environmental concerns that have been prioritized for EPA action. Action Plans have been published on the following groups:

*  Benzidine Dyes Released August 18, 2010

*  Bisphenol A (BPA) Released March 29, 2010

*  Hexabromocyclododecane (HBCD) Released August 18, 2010

*  Methylene Diphenyl Diisocyanate (MDI) and Related Compounds - particularly uncured MDI e.g., from spray foam, adhesives & coatings, released April 2011

*  Nonylphenol and Nonylphenol Ethoxylates (NPEs) Released August 18, 2010

*  Perfluorinated chemicals (PFCs) Released December 30, 2009

*  Penta, octa, and decabromodiphenyl ethers (PBDEs) in products Released December 30, 2009

*  Phthalates Released December 30, 2009. Note that the Action Plan specifically identifies 8 phthalates by CASRN for specific actions, but repeatedly identifies the entire class of dialkylortho-phthalates (or phthalate esters) as being of concern and targets of other actions.

*  Short-chain chlorinated paraffins Released December 30, 2009 (note EPA is asssessing medium and long chain chlorinated paraffins as well under this action plan, so Pharos includes all chlorinated paraffins

* Toluene Diisocyanate (TDI) and Related Compounds - particularly uncured MDI e.g., from spray foam, adhesives & coatings, released April 2011

Action Plans were released for each of these groups of chemicals outlining plans to establish regulations requiring significant risk reduction measures to protect human health and the environment.

Hazards for Hazard List
Endpoint Hazard Rating and Description GS Score HPD C2C
PBT (Persistence, Bioaccumulation & Toxicity)
PBT (Persistence, Bioaccumulation & Toxicity): Very high hazard
PBTs for Expedited Action to Reduce Risks
Developmental Toxicity incl. developmental neurotoxicity
Developmental Toxicity incl. developmental neurotoxicity: High hazard
Developmental Effects Reproductive Toxicity (Repro + Dev)
Developmental Toxicity incl. developmental neurotoxicity
Developmental Toxicity incl. developmental neurotoxicity: High hazard
Developmental toxicity - TSCA Criteria met Reproductive Toxicity (Repro + Dev)
Carcinogenicity
Carcinogenicity: High hazard
Known human carcinogen - TSCA Criteria met Carcinogenicity
Mutagenicity/Genotoxicity
Mutagenicity/Genotoxicity: High hazard
Mutagenicity - TSCA Criteria met Mutagenicity
Neurotoxicity-Single Exposure
Neurotoxicity-Single Exposure: High hazard
Neurobehavioral effects Neurotoxicity
Carcinogenicity
Carcinogenicity: High hazard
Probable human carcinogen - TSCA Criteria met Carcinogenicity
Reproductive Toxicity
Reproductive Toxicity: High hazard
Reproductive effects Reproductive Toxicity (Repro + Dev)
Reproductive Toxicity
Reproductive Toxicity: High hazard
Reproductive toxicity - TSCA Criteria met Reproductive Toxicity (Repro + Dev)
Acute Aquatic Toxicity
Acute Aquatic Toxicity: High hazard
Acute Aquatic toxicity - TSCA Criteria met Acute Aquatic Toxicity (Fish, Invertibrates, and/or Algae)
Skin Sensitization
Skin Sensitization: High hazard
Acute dermal toxicity - TSCA Criteria met Dermal Toxicity
Chronic Aquatic Toxicity
Chronic Aquatic Toxicity: High hazard
Chronic aquatic toxicity - TSCA Criteria met Chronic Aquatic Toxicity (Fish, Invertibrates, and/or Algae)
Systemic Toxicity/Organ Effects-Single Exposure
Systemic Toxicity/Organ Effects-Single Exposure: High hazard
Chronic cardiovascular, renal and musculoskeletal effects - TSCA Criteria met Oral, Dermal, and/or Inhalative Toxicity
Systemic Toxicity/Organ Effects-Single Exposure
Systemic Toxicity/Organ Effects-Single Exposure: High hazard
Chronic liver effects - TSCA Criteria met Oral, Dermal, and/or Inhalative Toxicity
Acute Mammalian Toxicity
Acute Mammalian Toxicity: High hazard
Chronic mammalian toxicity - TSCA criteria met Oral, Dermal, and/or Inhalative Toxicity
Neurotoxicity-Single Exposure
Neurotoxicity-Single Exposure: High hazard
Chronic nervous system and hepatic effects - TSCA Criteria met Neurotoxicity
Acute Mammalian Toxicity
Acute Mammalian Toxicity: High hazard
Chronic toxicity from inhalation exposures - TSCA Criteria met Inhalative Toxicity
Chronic Aquatic Toxicity
Chronic Aquatic Toxicity: High hazard
Highly toxic to aquatic organisms Chronic Aquatic Toxicity (Fish, Invertibrates, and/or Algae)
Respiratory Sensitization
Respiratory Sensitization: High hazard
Inhalation sensitizer causing asthma and lung damage Skin and Respiratory Sensitization
Neurotoxicity-Single Exposure
Neurotoxicity-Single Exposure: High hazard
Neurotoxicity - TSCA Criteria met Neurotoxicity
Respiratory Sensitization
Respiratory Sensitization: High hazard
Respiratory sensitizer - TSCA Criteria met Skin and Respiratory Sensitization
Acute Mammalian Toxicity
Acute Mammalian Toxicity: Moderate hazard
Acute mammallian toxicity - TSCA Criteria met Oral, Dermal, and/or Inhalative Toxicity
Acute Mammalian Toxicity
Acute Mammalian Toxicity: Moderate hazard
Acute toxicity from inhalation exposures - TSCA Criteria met Inhalative Toxicity
Carcinogenicity
Carcinogenicity: Moderate hazard
Limited evidence of carcinogenicity - TSCA Criteria met Carcinogenicity
Carcinogenicity
Carcinogenicity: Moderate hazard
Possible carcinogen - TSCA Criteria met Carcinogenicity
Carcinogenicity
Carcinogenicity: Moderate hazard
Potential carcinogenicity to specifc target organs - TSCA Criteria met Carcinogenicity
Restricted List
Restricted List: Potential concern hazard
Chemicals Removed or Consolidated from TSCA Work Plan Chemicals
Restricted List
Restricted List: Potential concern hazard
EPA Chemical of Concern - Action Plan published
Restricted List
Restricted List: Potential concern hazard
Signficant New Use Rule (SNUR) proposed
Restricted List
Restricted List: Potential concern hazard
SNUR (Significant New Use Rule)
Restricted List
Restricted List: Potential concern hazard
TSCA Work Plan chemical - Action Plan in development
Restricted List
Restricted List: Potential concern hazard
TSCA Work Plan chemical - ongoing chemical (risk) assessment
Restricted List
Restricted List: Potential concern hazard
TSCA Work Plan chemical – no action planned
Bioaccumulation
Bioaccumulation: Potential concern hazard
High bioaccumulation potential - TSCA Criteria met Bioaccumulation
Persistence
Persistence: Potential concern hazard
High environmental persistence - TSCA Criteria met Persistence
Bioaccumulation
Bioaccumulation: Potential concern hazard
Low bioaccumulation potential - TSCA Criteria met Bioaccumulation
Persistence
Persistence: Potential concern hazard
Low environmental persistence - TSCA Criteria met Persistence
Persistence
Persistence: Potential concern hazard
Medium environmental persistence - TSCA Criteria met Persistence
Bioaccumulation
Bioaccumulation: Potential concern hazard
Moderate bioaccumulation potential - TSCA Criteria met Bioaccumulation

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