CA EPA - Prop 65

Chemicals Known to the State to Cause Cancer or Reproductive Toxicity - California Proposition 65 - Safe Drinking Water and Toxic Enforcement Act Of 1986
In 1986, California voters approved an initiative to address their growing concerns about exposure...

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In 1986, California voters approved an initiative to address their growing concerns about exposure to toxic chemicals. That initiative became the Safe Drinking Water and Toxic Enforcement Act of 1986, better known by its original name of Proposition 65. Proposition 65 requires the State to publish a list of chemicals known to cause cancer or birth defects or other developmental or reproductive harm. This list has grown to include approximately 775 chemicals since it was first published in 1987.
A chemical in the Prop 65 list may be identified as known to cause cancer, damage to development or damage to the male or female reproductive system or any combination of these four health endpoints.
Proposition 65 requires businesses to notify Californians about significant amounts of chemicals in the products they purchase, in their homes or workplaces, or that are released into the environment. By providing this information, Proposition 65 enables Californians to make informed decisions about protecting themselves from exposure to these chemicals. Proposition 65 also prohibits California businesses from knowingly discharging significant amounts of listed chemicals into sources of drinking water.
The Office of Environmental Health Hazard Assessment (OEHHA) administers the Proposition 65 program. OEHHA, which is part of the California Environmental Protection Agency (Cal/EPA), also evaluates all currently available scientific information on substances considered for placement on the Proposition 65 list. Extraacted from "Proposition 65 in Plain Language (

UPDATES: Proposition 65 requires the Governor to publish a complete list at least annually. Additions, deletions and corrections are generally made several times per year. Changes are announced on the Proposition 65 listserve ( and on the Changes web page ( The most current list is available at both in PDF form and XCL. The XCL file can be sorted by date of listing.

NOT INCLUDED IN PHAROS: Any listing without a CAS number. HBN staff have assigned CAS numbers for some listings for which the state of CA has not.

California Environmental Protection Agency (CA EPA)