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G&L - Neurotoxic Chemicals

Developmental neurotoxicity of industrial chemicals, List of 201 Chemicals known to be neurotoxic in man

Medical journal article reviewing neurotoxicity literature and classifying 201 chemicals as...

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Medical journal article reviewing neurotoxicity literature and classifying 201 chemicals as neurotoxicants, developmental neurotoxicants and emerging neurotoxicants. The article does not list CAS numbers. HBN staff assigned the listing to CAS numbers.

Followup paper published February 15, 2014 (Lancet Neurol 2014; 13: 330–38) and lists 12 new neurotoxicants and 6 new developmental neurotoxicants.

Grandjean and Landrigan participated in the TENDR consensus statement (Environ Health Perspect; DOI:10.1289/EHP358), which lists additional developmental neurotoxicants. These will be included shortly:

  • Nitrogen dioxide (10102-44-0)
  • PAHs
  • Organophosphate (OP) pesticides
Hazards for Hazard List
Endpoint Hazard Rating and Description GREENSCREEN® HPD C2C
Developmental Toxicity incl. developmental neurotoxicity
Developmental Toxicity incl. developmental neurotoxicity: High to moderate hazard Low confidence
Developmental Neurotoxicant Priority List Reproductive Toxicity (Repro + Dev) (Red)
Developmental Toxicity incl. developmental neurotoxicity
Developmental Toxicity incl. developmental neurotoxicity: High to moderate hazard Low confidence
Developmental neurotoxicant (2014) Priority List Reproductive Toxicity (Repro + Dev)
Neurotoxicity-Single Exposure
Neurotoxicity-Single Exposure: High to moderate hazard Low confidence
Emerging neurotoxicant Neurotoxicity (Yellow or Green)
Neurotoxicity-Repeated Exposure
Neurotoxicity-Repeated Exposure: Very high to moderate hazard Low confidence
Known to be neurotoxic in man (2014) Neurotoxicity
Neurotoxicity-Repeated Exposure
Neurotoxicity-Repeated Exposure: Very high to moderate hazard Low confidence
Neurotoxic Neurotoxicity (Red or Yellow)

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