US EPA - IRIS Carcinogens

Integrated Risk Information System Database (IRIS)
Database of substances categorized by weight-of-evidence classifications established by EPA using...

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Database of substances categorized by weight-of-evidence classifications established by EPA using the 1986, 1996, 1999, and 2005 Guidelines for Carcinogen Risk Assessment. These guidelines reflect the evolution of the science in this area and the corresponding evolution of the Agency’s approach to characterizing weight-of-evidence for human carcinogenicity.

A small number of substances are of uncertain content and have no CAS number and are not currently included in the CML: such as Diesel Exhaust & Nickel refinery dust. Not all compound groups are fully populated

The 1986 Probable human carcinogen Group B1 is based on limited evidence of carcinogenicity in humans and sufficient evidence of carcinogenicity in animals. The Group B2 is based solely on sufficient evidence of carcinogenicity in animals.

(1999) Suggestive evidence of carcinogenicity fulle explain is "suggestive evidence of carcinogenicity, but not sufficient to assess human carcinogenic potential"

Agency
US Environmental Protection Agency (US EPA)
Updated
2018-01-04
Website
https://cfpub.epa.gov/ncea/iris/search/index.cfm?keyword=
Hazards for Hazard List
Endpoint Hazard Rating and Description GS Score HPD C2C
Carcinogenicity
H
(1986) Group A - Human Carcinogen LT-1 Priority List Carcinogenicity (Red)
Carcinogenicity
H
(1986) Group B1 - Probable human Carcinogen LT-1 Priority List Carcinogenicity (Red)
Carcinogenicity
H
(1986) Group B2 - Probable human Carcinogen LT-1 Priority List Carcinogenicity (Red)
Carcinogenicity
H
(1996) Known/likely human Carcinogen LT-1 Priority List Carcinogenicity (Red)
Carcinogenicity
H
(1999, 2005) Carcinogenic to humans LT-1 Priority List Carcinogenicity (Red)
Carcinogenicity
H
(1999, 2005) Likely to be Carcinogenic to humans LT-1 Priority List Carcinogenicity (Red)
Carcinogenicity
M
(1986) Group C - Possible human Carcinogen LT-UNK Priority List Carcinogenicity (Red)
Carcinogenicity
L
(1986) Group E - Evidence of non-carcinogenicity for humans LT-UNK Carcinogenicity (Green)
Carcinogenicity
L
(1996, 1999, 2005) Not likely to be carcinogenic to humans LT-UNK Carcinogenicity (Green)
Carcinogenicity
H-L
(2005) Suggestive evidence of Carcinogenic potential LT-UNK Carcinogenicity (Red, Yellow, or Green)
Carcinogenicity
H-L
(1986) Group D - Not classifiable as to human carcinogenicity LT-UNK Carcinogenicity (Red, Yellow, or Green)
Carcinogenicity
H-L
(1999) Suggestive evidence of carcinogenicity LT-UNK Carcinogenicity (Red, Yellow, or Green)
Carcinogenicity
H-L
(1996) Carcinogenic potential cannot be determined NoGS Carcinogenicity (Red, Yellow, or Green)
Carcinogenicity
H-L
(1999) Data are inadequate for an assessment of human carcinogenic potential NoGS Carcinogenicity (Red, Yellow, or Green)
Carcinogenicity
H-L
(2005) Inadequate information to assess carcinogenic potential NoGS Carcinogenicity (Red, Yellow, or Green)

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